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<h3>General Concepts</h3><hr>
<h3>General concepts</h3><hr>
* [[Nomenclature of Type III Secretion Systems|Nomenclature]]
* [[Nomenclature of Type III Secretion Systems|Nomenclature]]
* [[Flagellar T3SS vs. virulence-associated T3SS]]
* [[Flagellar T3SS vs. virulence-associated T3SS]]

Revision as of 12:17, 30 April 2019

Virulence-associated type III secretion systems (T3SS) serve the injection of bacterial effector proteins into eukaryotic host cells to manifest bacterial colonization and infection. Consequently, these systems are essential factors for the virulence of numerous animal and plant pathogens like Salmonella, Yersinia, enteropathogenic Escherichia coli (EPEC) or Pseudomonas. The macromolecular machine mediating secretion and injection of effector proteins is called injectisome or needle complex. This wiki aims at providing a comprehensive overview of all aspects of T3SS.


Components of the T3SS injectisome