Welcome to the T3SS Wiki!: Difference between revisions

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{{DISPLAYTITLE:Welcome to the T3SS Wiki}}
{{Main Page}}
Virulence-associated type III secretion systems (T3SS) serve the injection of bacterial [[Effectors|effector proteins]] into eukaryotic host cells to manifest bacterial colonization and infection. Consequently, these systems are essential factors for the virulence of numerous animal and plant pathogens like ''Salmonella'', ''Yersinia'', enteropathogenic ''Escherichia coli'' (EPEC) or ''Pseudomonas''. The macromolecular machine mediating secretion and injection of effector proteins is called injectisome or [[needle complex]]. This wiki aims at providing a comprehensive overview of all aspects of T3SS.
{| class="wikitable"
|+Components of the T3SS injectisome
| rowspan="20" |[[File:T3SS Overview.png|frameless|548x548px]]
|1
|SctC
|[[Secretin]]
|-
|2
|SctF
|[[Needle filament|Needle filament protein]]
|-
|3
|SctI
|[[Needle adapter|Needle adapter (inner rod) protein]]
|-
|4
|SctJ
|[[Inner ring|Inner inner ring protein]]
|-
|5
|SctD
|[[Inner ring|Outer inner ring protein]]
|-
|6
|SctK
|
|-
|7
|SctQ
|[[Sorting platform|Major sorting platform component]]
|-
|8
|SctL
|[[Stator]]
|-
|9
|SctN
|[[ATPase]]
|-
|10
|SctO
|[[Stalk]]
|-
|11
|SctR
|[[Export apparatus|Minor export apparatus protein]]
|-
|12
|SctS
|[[Export apparatus|Minor export apparatus protein]]
|-
|13
|SctT
|[[Export apparatus|Minor export apparatus protein]]
|-
|14
|SctU
|[[Switch protein]]
|-
|15
|SctV
|[[Export apparatus|Major export apparatus protein]]
|-
|16
|SctE
|[[Translocon|Translocon protein]]
|-
|17
|SctB
|[[Translocon|Translocon protein]]
|-
|18
|SctA
|[[Needle tip|Needle tip protein]]
|-
|19
|SctP
|[[Needle length regulator]]
|-
|20
|SctW
|[[Gatekeeper]]
|}
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